Brand Reference: Vascepa
| Metric | Verified Benchmark | Source |
|---|---|---|
| Icosapent Ethyl (Ultra-Pure EPA) RxNorm Concept ID | 1311080 | U.S. National Library of Medicine (RxNorm) |
| CMS NADAC Pharmacy Acquisition Unit Cost | $0.8900 / unit | CMS Medicaid NADAC Weekly Feed |
| Walk-In Chain Pharmacy Cash Average | $298.00 / mo | CMS NADAC + U.S. Retail Markup Index |
| Mark Cuban Cost Plus Wholesale Price | $46.50 / mo | Cost Plus Drugs Wholesale Feed |
| Community Mean Out-of-Pocket Paid | $54.00 / mo | 18 Zero-PHI Verified Patient Logs |
96%+ pure omega-3 eicosapentaenoic acid ethyl ester (devoid of LDL-raising DHA) that reduces hepatic VLDL-triglyceride synthesis, intercalates into endothelial phospholipid bilayers to quench lipid peroxidation, and generates specialized pro-resolving resolvins E1/E2.
Out-of-pocket price dispersion on Icosapent Ethyl (Ultra-Pure EPA) spans $46.50 to $298.00 per 30-day fill: pharmacy acquisition benchmarks sit near $0.8900/unit, allowing cash buyers bypassing PBM spread pricing to retain $251.50 each month (84% reduction).
With 89 hours plasma phospholipid EPA residence kinetics and De-esterified by pancreatic lipase; requires meal co-ingestion bioavailability, Icosapent Ethyl (Ultra-Pure EPA) undergoes mitochondrial beta-oxidation without cyp450 inhibition and establishes therapeutic activity over 4–8 weeks triglyceride and epa:aa ratio equilibrium.
Standard adult regimens span 2 grams PO twice daily with meals (4 g/day total). Prescribers screen specifically against severe hypersensitivity to fish or shellfish, while community micro-logs most frequently note mild bleeding/bruising tendency (7% of reports), arthralgia (5% of reports), atrial fibrillation (rare) (3% of reports).
Across 18 verified cash-pay logs, Icosapent Ethyl (Ultra-Pure EPA) achieves a 86.00% Worth-It rating with out-of-pocket spend averaging $54.00/mo versus $298.00/mo walk-in retail.
Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.
Switched to Cost Plus Drugs at 2 grams PO twice daily with meals (4 g/day total) for Icosapent Ethyl (Ultra-Pure EPA); monthly out-of-pocket dropped to $40.92 compared with $298.00 retail.
Completed 10 weeks on Icosapent Ethyl (Ultra-Pure EPA) (2 grams PO twice daily with meals (4 g/day total)). Zero notable side effects on steady dosing.
Consistent biomarker response on 2 grams PO twice daily with meals (4 g/day total) Icosapent Ethyl (Ultra-Pure EPA) sourced via Compounding ($53.94/mo cash pay without insurance prior authorization).