Uroselective Alpha-1A / Alpha-1D Adrenoceptor Antagonist • Rx

Tamsulosin Hydrochloride

Brand Reference: Flomax

Medically Reviewed by Dr. Julian Sterling, MD, FACS (NPI #1376841536)
83.50%
Patient “Worth It”
27 verified logs
$5.80
Lowest Monthly Cash

Tamsulosin Hydrochloride Clinical & Real-World Cost Fact Matrix

Metric Verified Benchmark Source
Tamsulosin Hydrochloride RxNorm Concept ID 77492 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $0.0560 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $38.00 / mo CMS NADAC + U.S. Retail Markup Index
Mark Cuban Cost Plus Wholesale Price $5.80 / mo Cost Plus Drugs Wholesale Feed
Community Mean Out-of-Pocket Paid $7.20 / mo 27 Zero-PHI Verified Patient Logs
INSTANT PRESCRIPTION & CASH ROUTING

Verified Online Prescribers & Wholesale Pharmacies for Tamsulosin Hydrochloride

DotMD Club Members get $29 flat-rate script renewals →
Mark Cuban Cost Plus Drugs (Wholesale Pharmacy)
Requires an existing doctor prescription. Need a script? Pair with a $29 DotMD Club TeleMed consult.
$5.80/mo
Wholesale Cash Price
View Wholesale Rx →
Ro Body & Metabolic Clinic (Online Doctor Consult + Delivery)
Asynchronous physician review included • Ships in ~2 days
$ 45.00
Consult / Starting Tier
Start Online Visit →
Hone Health Hormone & At-Home Biomarker Lab (Online Doctor Consult + Delivery)
Asynchronous physician review included • Ships in ~3 days
$ 65.00
Consult / Starting Tier
Start Online Visit →
Hims & Hers Direct Cash Pharmacy (Online Doctor Consult + Delivery)
Asynchronous physician review included • Ships in ~2 days • Rx included in monthly tier
$ 49.00
All-In Monthly
Start Online Visit →

Tamsulosin Hydrochloride Clinical Pharmacology & DailyMed Monograph

RxCUI 77492 • NDC 00378-0592-01

Preferentially blocks alpha-1A adrenoceptors (70% of prostatic smooth-muscle alpha receptors) over vascular alpha-1B receptors, relaxing bladder neck and prostatic urethral smooth-muscle tone to boost peak urinary flow without systemic blood pressure drop.

Out-of-pocket price dispersion on Tamsulosin Hydrochloride spans $5.80 to $38.00 per 30-day fill: pharmacy acquisition benchmarks sit near $0.0560/unit, allowing cash buyers bypassing PBM spread pricing to retain $32.20 each month (85% reduction).

With 9–13 hours (modified-release beads) residence kinetics and > 90% fasting / controlled-fed 30 min after same daily meal bioavailability, Tamsulosin Hydrochloride undergoes hepatic cyp3a4 and cyp2d6 oxidation plus conjugation and establishes therapeutic activity over 4–8 hours initial urinary flow gain; 2 weeks peak.

Standard adult regimens span 0.4 mg PO once daily 30 min after same meal, 0.8 mg PO once daily. Prescribers screen specifically against planned cataract phacoemulsification without surgeon alert (intraoperative floppy iris syndrome); severe sulfonamide anaphylaxis, while community micro-logs most frequently note retrograde/anejaculation (18% of reports), first-dose postural dizziness (9% of reports), rhinitis (8% of reports).

Half-Life
9–13 hours (modified-release beads)
Bioavailability
> 90% fasting / controlled-fed 30 min after same daily meal
Metabolism & Clearance
Hepatic CYP3A4 and CYP2D6 oxidation plus conjugation
Clinical Onset
4–8 hours initial urinary flow gain; 2 weeks peak

Standard Adult Titration & Dosages

0.4 mg PO once daily 30 min after same meal 0.8 mg PO once daily

Absolute & Relative Contraindications

  • Planned cataract phacoemulsification without surgeon alert (intraoperative floppy iris syndrome)
  • Severe sulfonamide anaphylaxis

Logged Side-Effect Incidence (27 Reports)

Retrograde/anejaculation 18%
First-dose postural dizziness 9%
Rhinitis 8%

Tamsulosin Hydrochloride Patient Dosage Logs & Out-of-Pocket Cost Ledger

Across 27 verified cash-pay logs, Tamsulosin Hydrochloride achieves a 83.50% Worth-It rating with out-of-pocket spend averaging $7.20/mo versus $38.00/mo walk-in retail.

15-Second Anonymous Micro-Log (Zero-PHI Architecture)

Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.

Effectiveness: 5/5 • Worth It Dosage: 0.4 mg PO once daily 30 min after same m • Paid: $5.10/mo via Cost Plus Drugs
Retrograde/anejaculation

Switched to Cost Plus Drugs at 0.4 mg PO once daily 30 min after same meal for Tamsulosin Hydrochloride; monthly out-of-pocket dropped to $5.10 compared with $38.00 retail.

Effectiveness: 5/5 • Worth It Dosage: 0.8 mg PO once daily • Paid: $5.92/mo via Compounding

Completed 10 weeks on Tamsulosin Hydrochloride (0.8 mg PO once daily). Zero notable side effects on steady dosing.

Effectiveness: 4/5 • Worth It Dosage: 0.4 mg PO once daily 30 min after same m • Paid: $6.73/mo via Cash Clinic
Rhinitis

Consistent biomarker response on 0.4 mg PO once daily 30 min after same meal Tamsulosin Hydrochloride sourced via Cash Clinic ($6.73/mo cash pay without insurance prior authorization).