Brand Reference: Prinivil, Zestril
| Metric | Verified Benchmark | Source |
|---|---|---|
| Lisinopril RxNorm Concept ID | 29046 | U.S. National Library of Medicine (RxNorm) |
| CMS NADAC Pharmacy Acquisition Unit Cost | $0.0240 / unit | CMS Medicaid NADAC Weekly Feed |
| Walk-In Chain Pharmacy Cash Average | $18.00 / mo | CMS NADAC + U.S. Retail Markup Index |
| Mark Cuban Cost Plus Wholesale Price | $4.80 / mo | Cost Plus Drugs Wholesale Feed |
| Community Mean Out-of-Pocket Paid | $5.50 / mo | 29 Zero-PHI Verified Patient Logs |
Hydrophilic active dipeptide mimetic that chelates the catalytic zinc ion of pulmonary and endothelial ACE, halting conversion of angiotensin I to angiotensin II while preserving vasodilatory bradykinin.
For self-pay patients filling Lisinopril (NDC 00378-2074-01), direct wholesale and telehealth fulfillment drops monthly spend from $18.00 retail to $4.80 (73% savings against a $0.0240 CMS pharmacy acquisition baseline).
Clinical clearance of Lisinopril (Non-Prodrug Lysine Angiotensin-Converting Enzyme (ACE) Inhibitor) relies on zero hepatic metabolism; 100% excreted unchanged by glomerular filtration with a 12 hours half-life; patients absorbing at 25% oral (unaffected by food) bioavailability typically observe target onset around 1 hour onset; 6 hours peak.
FDA clinical labeling for Lisinopril restricts administration in hereditary or prior ace-inhibitor angioedema; sacubitril/valsartan within 36 hours; pregnancy across 5 mg PO daily, 10 mg PO daily, 20 mg PO daily, 40 mg PO daily, with self-reported patient tracking dominated by dry bradykinin cough (14% of reports), dizziness (7% of reports), potassium rise (4% of reports).
Across 29 verified cash-pay logs, Lisinopril achieves a 82.30% Worth-It rating with out-of-pocket spend averaging $5.50/mo versus $18.00/mo walk-in retail.
Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.
Switched to Cost Plus Drugs at 5 mg PO daily for Lisinopril; monthly out-of-pocket dropped to $4.50 compared with $18.00 retail.
Completed 10 weeks on Lisinopril (10 mg PO daily). Zero notable side effects on steady dosing.
Consistent biomarker response on 20 mg PO daily Lisinopril sourced via Cash Clinic ($5.57/mo cash pay without insurance prior authorization).