Dual Type I, II & III 5-Alpha-Reductase Pan-Inhibitor • Rx

Dutasteride

Brand Reference: Avodart

Medically Reviewed by Dr. Priya Nair, MD, FAAD (NPI #1295730425)
90.20%
Patient “Worth It”
34 verified logs
$7.90
Lowest Monthly Cash

Dutasteride Clinical & Real-World Cost Fact Matrix

Metric Verified Benchmark Source
Dutasteride RxNorm Concept ID 228790 U.S. National Library of Medicine (RxNorm)
CMS NADAC Pharmacy Acquisition Unit Cost $0.1350 / unit CMS Medicaid NADAC Weekly Feed
Walk-In Chain Pharmacy Cash Average $98.00 / mo CMS NADAC + U.S. Retail Markup Index
Mark Cuban Cost Plus Wholesale Price $7.90 / mo Cost Plus Drugs Wholesale Feed
Community Mean Out-of-Pocket Paid $11.00 / mo 34 Zero-PHI Verified Patient Logs
INSTANT PRESCRIPTION & CASH ROUTING

Verified Online Prescribers & Wholesale Pharmacies for Dutasteride

DotMD Club Members get $29 flat-rate script renewals →
Mark Cuban Cost Plus Drugs (Wholesale Pharmacy)
Requires an existing doctor prescription. Need a script? Pair with a $29 DotMD Club TeleMed consult.
$7.90/mo
Wholesale Cash Price
View Wholesale Rx →
Ro Body & Metabolic Clinic (Online Doctor Consult + Delivery)
Asynchronous physician review included • Ships in ~2 days
$ 45.00
Consult / Starting Tier
Start Online Visit →
Hone Health Hormone & At-Home Biomarker Lab (Online Doctor Consult + Delivery)
Asynchronous physician review included • Ships in ~3 days
$ 65.00
Consult / Starting Tier
Start Online Visit →
Hims & Hers Direct Cash Pharmacy (Online Doctor Consult + Delivery)
Asynchronous physician review included • Ships in ~2 days • Rx included in monthly tier
$ 49.00
All-In Monthly
Start Online Visit →
Board-Certified Teledermatology Compounding (Online Doctor Consult + Delivery)
Asynchronous physician review included • Ships in ~3 days
$ 20.00
Consult / Starting Tier
Start Online Visit →

Dutasteride Clinical Pharmacology & DailyMed Monograph

RxCUI 228790 • NDC 00378-4650-93

Inhibits both sebaceous/dermal Type I and follicular/prostatic Type II 5-alpha-reductase with 45x greater Type I and 2.5x greater Type II potency than finasteride—suppressing serum DHT by >93% and scalp DHT by ~51% vs ~41% on finasteride.

For self-pay patients filling Dutasteride (NDC 00378-4650-93), direct wholesale and telehealth fulfillment drops monthly spend from $98.00 retail to $7.90 (92% savings against a $0.1350 CMS pharmacy acquisition baseline).

Clinical clearance of Dutasteride (Dual Type I, II & III 5-Alpha-Reductase Pan-Inhibitor) relies on hepatic cyp3a4 and cyp3a5 hydroxylation; fecal elimination with a ~5 weeks (35 days steady-state depot) half-life; patients absorbing at 60% softgel oral bioavailability typically observe target onset around 1–2 weeks >85% dht suppression; 4–6 months vertex density gain.

FDA clinical labeling for Dutasteride restricts administration in pregnancy / women of childbearing potential; blood donation prohibited for 6 months after last capsule across 0.5 mg PO 2–3x weekly (intermittent alopecia protocol), 0.5 mg PO once daily, with self-reported patient tracking dominated by dry scalp sebum reduction (9% of reports), libido attenuation (7% of reports), breast tenderness (3% of reports).

Half-Life
~5 weeks (35 days steady-state depot)
Bioavailability
60% softgel oral
Metabolism & Clearance
Hepatic CYP3A4 and CYP3A5 hydroxylation; fecal elimination
Clinical Onset
1–2 weeks >85% DHT suppression; 4–6 months vertex density gain

Standard Adult Titration & Dosages

0.5 mg PO 2–3x weekly (intermittent alopecia protocol) 0.5 mg PO once daily

Absolute & Relative Contraindications

  • Pregnancy / women of childbearing potential
  • Blood donation prohibited for 6 months after last capsule

Logged Side-Effect Incidence (34 Reports)

Dry scalp sebum reduction 9%
Libido attenuation 7%
Breast tenderness 3%

Dutasteride Patient Dosage Logs & Out-of-Pocket Cost Ledger

Across 34 verified cash-pay logs, Dutasteride achieves a 90.20% Worth-It rating with out-of-pocket spend averaging $11.00/mo versus $98.00/mo walk-in retail.

15-Second Anonymous Micro-Log (Zero-PHI Architecture)

Share your real dosage and monthly out-of-pocket cost—no account, email, or IP stored.

Effectiveness: 5/5 • Worth It Dosage: 0.5 mg PO 2–3x weekly (intermittent alop • Paid: $6.95/mo via Cost Plus Drugs
Libido attenuation

Switched to Cost Plus Drugs at 0.5 mg PO 2–3x weekly (intermittent alopecia protocol) for Dutasteride; monthly out-of-pocket dropped to $6.95 compared with $98.00 retail.

Effectiveness: 5/5 • Worth It Dosage: 0.5 mg PO once daily • Paid: $8.06/mo via Local Pharmacy

Completed 10 weeks on Dutasteride (0.5 mg PO once daily). Zero notable side effects on steady dosing.

Effectiveness: 4/5 • Worth It Dosage: 0.5 mg PO 2–3x weekly (intermittent alop • Paid: $9.16/mo via TeleMed
Breast tenderness

Consistent biomarker response on 0.5 mg PO 2–3x weekly (intermittent alopecia protocol) Dutasteride sourced via TeleMed ($9.16/mo cash pay without insurance prior authorization).